南京邦诺生物科技有限公司

 

1.红霉素能影响细菌的蛋白合成，一般对革兰阳性菌有效，主要用于治疗耐青霉素G的金色葡萄球菌引起的感

染。

 

2.红霉素是常用的大环内酯类抗生素，抗菌谱与青霉素相似，主要用于对青霉素过敏患者，或对青霉素耐

药的金葡菌感染，亦可用于链球菌、肺炎球菌的感染及白喉带菌者。

 

3.本品为大环内酯类抗生素衍生物中间体属抑菌型抗生素，抗菌谱与青菌素相似，对口腔拟杆菌、产黑拟

杆菌、消化球菌、消化链球菌、痤疮丙酸杆菌等厌氧菌以及脑炎弓形体、衣原体、梅毒螺旋体等也有较好的抗菌作用。对螺旋杆菌、淋球菌、脑膜炎球菌、百日咳杆菌等作用较弱。 

 

4.适应症：适用于支原体肺炎、沙眼衣原体引起的新生儿结膜炎、婴儿肺炎、生殖泌尿道感染（包括非淋病性尿道炎

）、军团菌病、白喉（辅助治疗）及白喉带菌者、皮肤软组织感染、百日咳、敏感菌（流感杆菌、肺炎球菌、溶血性链球菌、葡萄球菌等）引起的呼吸道感染（包括肺炎）、链球菌咽峡炎、李斯德菌感染、风湿热的长期预防及心内膜炎的预防、空肠弯曲菌肠炎，以及淋病、梅毒、痤疮等。

 

5.临床上主要用于耐青霉素的金黄色葡萄球菌感染及对青霉素过敏的金黄色葡萄球菌感染。亦用于溶血性链球菌及肺炎球菌所致的呼吸道、军团菌肺炎、支原体肺炎、皮肤软组织等感染，此外，对白喉病人，以该品及白喉抗毒素联用则疗效显著。

 

中文别名:红霉素碱;红霉素A;红霉素(药用级);麦冬提取物4 : 1;红霉素,红霉素碱;艾狄密新

英文名称:Erythromycin

CAS:114-07-8

EINECS:204-040-1

分子式:C37H67NO13

分子量:733.93

熔点 133-135 °C

比旋光度 -74.5 o (c=2, ethanol)

折射率 -74 ° (C=2, EtOH)

溶解度 ethanol: soluble

沸点：818.4°C at 760 mmHg

闪点：448.8°C

蒸汽压：4.94E-31mmHg at 25°C 

性状: 白色或类白色结晶性粉末。呈弱碱性， 无臭，味苦

纯度：99%以上

包装：25kg/纸板桶

 

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Erythromycin (API) CAS # 114-07-8

 

1. Erythromycin can affect the protein synthesis of bacteria, generally Gram-positive bacteria, mainly for flu treatment of Staphylococcus aureus resistant to penicillin G caused

dye.

 

2. Erythromycin is commonly used macrolide antibiotics, antibacterial spectrum similar to penicillin, mainly used for patients allergic to penicillin or penicillin-resistant

S. aureus infection drugs, can be used for streptococci, pneumococcal infections and diphtheria carriers.

 

3. This product is a macrolide antibiotic derivative intermediate type genus antibacterial antibiotics, antibacterial spectrum and is similar to the Green streptozotocin, oral Bacteroides, Black intends to produce

Bacteria, digestive bacteria, digestion Streptococcus, Propionibacterium acnes and other anaerobic bacteria encephalitis toxoplasma, chlamydia, syphilis, also has a good antibacterial effect. On pylori, Neisseria gonorrhoeae, meningococcal, pertussis and so weak.

 

4. Indications: for mycoplasma pneumonia, neonatal conjunctivitis caused by Chlamydia trachomatis, infant pneumonia, genitourinary tract infections (including Ngu

), Legionella disease, diphtheria (adjuvant therapy) and diphtheria carriers, skin and soft tissue infections, whooping cough, sensitive bacteria (Haemophilus influenzae, Streptococcus pneumoniae, hemolytic streptococcus, staphylococcus, etc.) caused by respiratory infections (including pneumonia), a chain cocci angina, Li Side infection, long-term prevention of rheumatic fever and endocarditis prevention, Campylobacter jejuni enteritis, as well as gonorrhea, syphilis, and acne.

 

5. Clinical mainly used for penicillin-resistant Staphylococcus aureus infections and allergic to penicillin of Staphylococcus aureus infection. Respiratory tract and also for hemolytic streptococcus pneumonia caused by bacteria, Legionella pneumonia, Mycoplasma pneumonia, skin and soft tissue infections, in addition to diphtheria patient to the goods and diphtheria antitoxin combined with the significant effect.

 

Chinese alias: erythromycin base; erythromycin A; erythromycin (pharmaceutical grade); Radix extract 4: 1; erythromycin, erythromycin base; Aidi new secret

English name: Erythromycin

CAS: 114-07-8

EINECS: 204-040-1

Molecular formula: C37H67NO13

Molecular Weight: 733.93

Melting point 133-135 ° C

Specific rotation -74.5 o (c = 2, ethanol)

Refractive -74 ° (C = 2, EtOH)

Solubility ethanol: soluble

Boiling point: 818.4 ° C at 760 mmHg

Flash Point: 448.8 ° C

Vapor Pressure: 4.94E-31mmHg at 25 ° C

Traits: white or white crystalline powder. Weakly alkaline, odorless, bitter taste

Purity: 99% or more

Packing: 25kg / drum