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您当前的位置:首页 » 新闻中心 » 生产出口非那西丁(原料药)CAS#62-44-2
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生产出口非那西丁(原料药)CAS#62-44-2
发布时间:2016-08-29 16:54        浏览次数:8        返回列表
 出口非那西丁(原料药)CAS#62-44-2
 
中国于1954年开始生产非那西丁,由硝基氯苯与乙醇进行醚化反应得对硝基苯乙醚,再还原成对氨基苯乙醚后与乙酸进行乙酰化反应制得。
 
非那西丁解热镇痛作用与“乙酰水杨酸”相似,主要用作解热镇痛药,作用缓慢而持久,对治疗头痛、神经痛、关节痛和发热等都有较好疗效,但抗风湿、消炎作用较弱。剂量过大可导致高铁血红蛋白症,造成机体缺氧,长期用药可损害肾脏,甚至引起乳头坏死,应慎用。因其毒副作用和其他同类药物的迅速发展,该药已停止单独使用,只是作为原料药和其他药物配复方制剂。
 
中文同义词: 非那西汀;乙酰对氨基苯乙醚;乙酰乙氧基苯胺;对乙酰乙氧基苯胺;对乙酰氨基苯乙醚;非那西丁;4-乙氧基乙酰苯胺 
英文名称: Phenacetin 
 
CAS号: 62-44-2 
分子式: C10H13NO2 
分子量: 179.22 
EINECS号: 200-533-0 
 
性质  白色有光泽的鳞片状结晶或白色结晶性粉末。
纯度:99%以上
包装:25KG/纸板桶
熔点137-138℃,
折光率1.571。
质量标准:部颁标准或英国药典BP68版
用途:解热镇痛药,用于治疗发热头痛、神经痛等 
 
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Export phenacetin (API) CAS # 62-44-2
 
Chinese Synonyms: phenacetin; acetyl amino phenyl ether; ethoxy acetyl aniline; acetyl-ethoxy aniline; of acetaminophen ether; phenacetin; 4-ethoxy-acetanilide
English name: Phenacetin
 
CAS: 62-44-2
Molecular formula: C10H13NO2
Molecular Weight: 179.22
EINECS Number: 200-533-0
 
Nature shiny white scaly crystal or white crystalline powder.
Purity: 99% or more
Packing: 25KG / drum
Melting point 137-138 ℃,
Refractive index of 1.571.
Quality Standard: ministerial standard version or the British Pharmacopoeia BP68
Uses: anti-inflammatory drugs for the treatment of fever, headache, neuralgia
 
Phenacetin antipyretic and analgesic effects and "acetylsalicylic acid" similar, mainly used as anti-inflammatory drugs, slow and long-lasting effect on the treatment of headache, neuralgia, joint pain and fever have a good effect, However, anti-rheumatic, anti-inflammatory effect is weak. Overdose can cause methemoglobinemia, resulting in hypoxia, long-term medication can damage the kidneys, and even cause papillary necrosis, it should be used with caution. Because of the rapid development of side effects and other similar drugs, the drug has been discontinued alone, just as the drug and other pharmaceutical compound preparation.
 
China in 1954 began producing phenacetin, nitro chlorobenzene and ethanol ether reacted nitrobenzene, and then restore phenetidine paired with acetic acid after acetylation reaction.
 
标题:生产出口非那西丁(原料药)CAS#62-44-2
网址:http://bn2016.kuqiw.cn/news/itemid-81422.shtml